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Delirium in Older Persons

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Sharon K. Inouye, M.D., M.P.H. N Engl J Med 2006; 354:1157-1165 March 16, 2006 DOI: 10.1056/NEJMra052321 Share:

The prevalence of delirium increases sharply with age, and about 20 percent of older patients have delirium at the time of hospital admission for any reason. This review summarizes the clinical manifestations of and risk factors for delirium and the evaluation of patients with this condition. It includes an update on the current understanding of the pathogenesis of delirium and provides guidance regarding practical measures to prevent this common complication.

Supported in part by grants (R21AG025193 and K24AG00949) from the National Institute on Aging.

MEDIA IN THIS ARTICLE

FIGURE 1

Prevention and Management of Delirium in the Older Hospitalized Patient.

TABLE 1

No potential conflict of interest relevant to this article was reported. This article is dedicated to the memory of Joshua Bryan Inouye Helfand. I am indebted to Dr. Joseph Agostini for his helpful review of the manuscript and to Sarah Dowal and Patty Fugal for their assistance with the preparation of the manuscript. Clinical Features of Delirium.

SOURCE INFORMATION ARTICLE ACTIVITY

From the Department of Medicine, Harvard Medical School, Boston. Address reprint requests to Dr. Inouye at the Aging Brain Center, Hebrew Senior Life, 1200 Centre St., Boston, MA 02131.

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Delirium in Older Persons - NEJM —

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